In addition, this tumor demonstrates areas of degeneration and necrosis yellowish foci. Warthin s tumor, also known as papillary cystadenoma lymphomatosum, is a benign cystic tumor of the salivary glands containing abundant lymphocytes and germinal centers lymph nodelike stroma. This parotidian tumor occurs most often in smokers, in middleaged and older men. If you have problems viewing pdf files, download the latest version of adobe reader. The mean age of the subjects with warthin s tumor was 59. On microscopic histopathological analysis, papillae, fibrous capsule, and cystic spaces are characteristic findings of warthin s tumor. Bilateral and multifocal warthins tumor of parotid gland. Warthin s tumor is a relatively rare and generally benign neoformation whose incidence is second only to the pleomorphic adenoma. Is warthin s tumour of the parotid gland a lymph node disease. Twelve patients underwent ct plain scan, of which, 10 received the further enhancement. On gross pathology, cystic and multicentric appearance are characteristic findings of warthin s tumor. This entails the risk of a general anaesthetic and those pertaining.
You may purchase original highresolution image without pathpedia logo using our automated system that grants singleuser and multiuser, nonroyaltybased. Is warthins tumour of the parotid gland a lymph node. Discussion warthin tumor is a well encapsulated tumor and easily differentiates from adjacent tissues. Cigarette smoking and warthins tumor semantic scholar.
All structured data from the file and property namespaces is available under the creative commons cc0 license. Type c can be found in high cellularitys pleomorphic adenomas or malignant lesions. Warthin s tumor is the second most frequent benign tumor of the parotid gland the first one is pleomorphic adenoma. The first symptom is usually a painless, slowgrowing bump in front of the ear, on the bottom of the mouth, or under the chin. Warthin s tumor arises from salivary gland epithelium, which are secretory cells of the salivary gland. Ct and mri findings of parotid warthins tumors springerlink. Papillary cystadenoma lymphomatosum is a benign hamartoma or reactive proliferation of ductal salivary gland cells and lymphoid elements. Warthins tumor is second only to the pleomorfic adenoma and it usually affects people in their fifties and sixties. Warthin s tumor is an adenoma composed of bilayered columnar and basaloid oncocytic epithelium that forms multiple cysts with numerous papillae, accompanied by a proliferation of folliclecontaining lymphoid tissue. Unlike pleomorphic adenomas, warthin s tumor presents less than 1% risk of malignant evolution 5. The definitive diagnosis was adenocarcinoma arising in a warthins tumor. Pdf mucoepidermoid carcinoma in warthin tumor of the. It is named for pathologist aldred scott warthin, who described two cases in 1929. Warthin tumor is typically tannish brown, often with cystic spaces.
Warthins tumor represents the 514% of the neoplasias of the parotid and the 25% of the submaxillary ones3. Warthin tumor genetic and rare diseases information. It is usually located at the inferior pole of the gland and multicentric occurrence is seen more often with warthin s tumor than with any other salivary gland tumor. Surgical procedure for warthins tumor in the parotid gland. The parotid gland is the one most frequently struck by this type of neoplasia 84% figure 1. Warthin s tumor has an excellent prognosis due to the low rate of recurrence after surgical treatment. Ct provides reliable information about the location of the tumor.
It is most commonly encountered in male smokers in the fifth to seventh decades of life. Written informed consent was also obtained from the patient who is presented in this paper. Usual symptoms include swollen salivary gland, lump near the back of the lower jaw, jaw pain, the sensation of pressure, facial nerve paralysis, tinnitus, impaired hearing, an earache, etc. Sixty patients with warthin s tumor in the parotid gland who presented at the kansai medical university hospital from 1990.
Warthin s tumour shows multiple cysts that have numerous papillations covered by bilayered columnar and basaloid oncocytic epithelium. Surgical treatment strategy in warthin tumor of the parotid. Current controversies in the management of warthin tumour. Pdf warthin tumor was first described in the american literature, by aldred warthin, in 1929, the pathologist who named this tumor papillary. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126. A total of 143 96 percent of the warthin s tumors occurred in whites, and six 4 percent occurred in blacks. Mucoepidermoid carcinoma in warthin tumor of the parotid gland article pdf available in archives of medical science 1. Multifocal occurrence of warthins tumor in both parotid. Diagnostic value of mr imaging of parotid gland tumors. Warthin tumour is the second most common benign neoplasm of the parotid gland. Very rarely, warthin s tumor can also mimic malignant or metastatic disease by presenting within cervical. It is the second most common benign parotid gland tumor and accounts for 4% to 25% of all salivary gland tumors. Warthins tumor free download as powerpoint presentation. Xray, computed tomography ct scan, and magnetic resonance.
Although its aggressiveness has not been a concern, surgical resection remains the most common treatment modality. Facial nerve abnormality on parotidectomy for warthin. Ct and mri findings of 14 patients with pathologicallyconfirmed warthin s tumor 10 males and 4 females were retrospectively analyzed. The presence of multiple large cystic spaces is characteristic of this lesion.
We present a case of an 80yearold caucasian woman, who presented in our ent department because o f a progressive swelling in the left parotid gland. Warthins tumor corresponds to the cystic part of the specimen. Reported a case of large, bilateral, multiple warthins tumors of the parotid glands. Warthin s tumor is the second most common benign lesion of the parotid gland. Warthin s tumors as well as carcinomas can show the type b curve. Large and multiple warthins tumors of bilateral parotid glands.
In 46% of cases warthin s tumors occur bilaterally or two or more. Uniquely, among benign lesions of the parotid gland, it can be seen bilaterally in 710% of cases. Doctor answers on symptoms, diagnosis, treatment, and more. Warthin tumors are the second most common benign tumors of the parotid gland. Large, bilateral warthins tumor of the parotid gland is clinically very rare. Warthin s tumor is a type of benign tumor of the salivary glands. For language access assistance, contact the ncats public information officer. Warthin s tumor papillary cystadenoma lymphomatosum is a wellknown benign tumor of the parotid gland.
Most of cases are represented by a single localization, while only a small percentage of patients presents bilateral lesions or unilateral multifocal pattern. Gross appearance of warthin tumor of parotid gland. It has a low rate of growth and exhibits malignant transformation in 0. Warthin s tumor is the second most common benign neoplasm of the parotid. Any cancer thats not treated with an appropriate scientific modality surgery, radiation, andor chemotherapy as appropriate, will kill you.
Warthin s tumor is benign and exclusively involves the parotid gland but may, however, often show multifocal andor bilateral growth. Adenocarcinoma arising in a warthins tumor sciencedirect. The aim of this study was to evaluate the surgical procedure for removal of this tumor. Aldred scott warthin, who was the first pathologist to described it. Eur rev med pharmacol warthins tumor of parotid gland. Department of otolaryngology, head and neck surgery. Surgical treatment strategy in warthin tumor of the. Normally, the parotid gland has glandular cells that make enzymes that help to break down food, as well as tiny ducts lined by epithelial cells that carry those enzymes. Files are available under licenses specified on their description page. Warthin s tumour papillary cystadenoma lymphomatosum pcl constitutes a minority of salivary gland neoplasms and it is a monomorphic adenoma which primarily involves the parotid gland.
That is why surgery is not necessary when the preoperative diagnosis is certain and surgery should be avoided as often as possible because of the risk of. They are most common in parotid glands and around 11% of all benign salivary gland tumors. Alternative treatments for warthins tumor answers on. Kamrava on alternative treatments for warthins tumor. A vasoconstrictor was injected, with skin incision and platysma incision done followed by tissue dissection to expose the. This study was a retrospective analysis of 43 cases of parotid tumors.
Warthin tumor is a benign tumor of the salivary gland. Cresce lentamente como uma massa firme e indolor na bochecha. Warthins tumor, or warthin tumor, is a benign slowgrowing tumor of the parotid gland named for dr. Warthin tumors may increase in size over time, but few become cancerous.
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